However, in some cases, stopping Eliquis can increase your risk of side effects. Treatment and home management for blood clots, How to tell if it is a bruise or a blood clot, Blood-thinning foods, drinks, and supplements, help prevent DVT and PE from occurring again after the initial clot has been treated, help prevent DVT and PE after hip or knee replacement surgery, Spinal blood clots with spinal procedures., Increased risk of blood clots if Eliquis treatment is stopped early., have had past spinal surgery or problems with your spine, have had difficult or repeated spinal procedures in the past, have an epidural catheter (thin tube placed into your spine to deliver medication), bleeding that takes longer than usual to stop, menstrual periods that are heavier than usual or last longer than usual, avoiding contact sports and other sports with a risk of injury, wearing gloves when using tools such as knives or scissors, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your mouth, tongue, or throat, which can make it hard to breathe. Before starting Eliquis treatment, tell your doctor if you have triple-positive APS. A boxed warning is a serious warning from the Food and Drug Administration (FDA). Learn more below. Your doctor will tell you when you should stop taking ELIQUIS and when you may start taking it again. Reduce the risk of forming a blood clot in the legs (DVT) and lungs (PE) of people who have just had hip or knee replacementsurgery. Besides talking with your doctor, you can do some research on your own. Taking a blood thinner as part of your AFib treatment can reduce your risk of blood clots and stroke. Be sure to seek medical attention right away if you have signs or symptoms of bleeding such as unexpected bleeding or bleeding that lasts a long time. Introduction: Rivaroxaban is a novel oral anticoagulant with several indications, one of which is for stroke prevention in nonvalvular atrial fibrillation. Tell your doctor if you have any upcoming surgeries or dental procedures while youre taking Eliquis. Before taking Eliquis, there are certain precautions to consider. Other factors may also affect whether Eliquis is a good treatment option for you. If you have a blood disorder called triple-positive APS, you may have a raised risk of blood clots with Eliquis. These are just a few of the more common side effects reported by people who took Eliquis in clinical trials: * For more information about this side effect, see Side effect specifics below. For example, you may consider: Additionally, you should tell any healthcare professionals who treat you that youre taking Eliquis. Eliquis hasnt been reported to cause kidney-related side effects, such as kidney damage or reduced kidney function. If you have concerns about risk of spinal blood clots during Eliquis treatment, talk with your doctor or pharmacist. This is to reduce your risk of bleeding. If the side effects seem life threatening or you think youre having a medical emergency, immediately call 911 or your local emergency number. [Text HELP to 69108 for help.] ELIQUIS can cause bleeding, which can be serious, and rarely may lead to death. However, if your doctor has directed you to take low-dose aspirin to prevent heart attack or stroke (usually 81-162 milligrams a day), you should continue taking the aspirin unless your doctor instructs you otherwise. More severe drug rashes, such as erythroderma, may cause permanent changes to skin pigmentation after treatment. You may notice small, raised or flat lesions on reddened skin. Talk to your healthcare team before any surgery, medical, or dental procedures. Learn more about some of the side effects that Eliquis may cause. You can learn more about how we ensure our content is accurate and current by reading our. For more information about Eliquis, including details about its uses, see this in-depth article. Get medical help right away if you have any of the following symptoms: Sudden chest pain or chest tightness Sudden swelling of your face or tongue Trouble breathing Wheezing Some people may experience mild to serious side effects during their Eliquis treatment. Do not share this medication with others. Refill your prescription before you run out. Call your doctor for medical advice about side effects. Its not known whether its safe for people with an artificial heart valve to take Eliquis. The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a healthcare provider. Data obtained from you in connection with your registration for, and use of, this service may include your phone number and related carrier information. Eliquis has a boxed warning for the risk of spinal blood clots with spinal procedures. If youre concerned about weight gain while taking Eliquis, talk with your doctor. If you develop a rash after starting a new drug, you may be suspicious that your medication is causing this skin reaction. Also, if you take Eliquis to help prevent blood clots after hip or knee replacement surgery, you may have reduced mobility both before and after the surgery. Ask your doctor about the benefits and risks before any spinal procedure. Symptoms of blood clots in your spine include: Before having any spinal procedures done, tell your doctor that youre taking Eliquis. You are encouraged to report negative side effects of prescription drugs to the FDA. Bleeding disorders. If you have minor bleeding that happens frequently or is bothersome, talk with your doctor. You may have a higher risk of bleeding if you take blood thinners and take other medicines that increase your risk of bleeding. You can stop taking Eliquis without tapering your dosage first. Tell your doctor right away if you have any signs of serious bleeding, including: nosebleeds that happen often or don't stop, unusual tiredness/weakness, unusual pain/swelling/discomfort, unusual bruising, prolonged bleeding from cuts or gums, unusually heavy/prolonged menstrual flow, pink/dark urine, coughing up blood, vomit that is bloody or looks like coffee grounds, severe headache, dizziness/fainting, bloody/black/tarry stools, difficulty swallowing. And dont stop taking Eliquis unless your doctor recommends it. In clinical trials, some people taking Eliquis reported having blood in their urine, which could be a sign of bleeding in the kidneys. * This clot may press on your spinal cord, which could cause long lasting or permanent paralysis. In the United States, apixaban is also approved to treat certain types of blood clots (deep vein thrombosis-DVT, pulmonary embolus-PE) and to prevent them from forming again. The list below may not include all possible serious side effects of the drug. In the early stages, DIC causes your blood to clot excessively. This data may be used, For help, text HELP to 69108 or contact your mobile carrier. Dont stop taking Eliquis without first talking with your doctor. Eliquis has a boxed warning for the risk of spinal blood clots from certain spinal procedures. A drug allergy is an allergic reaction to a medication. Please see Full Prescribing Information, including Boxed WARNINGS and Medication Guide. You may have a higher risk of bleeding if you take ELIQUIS with other medicines that increase your risk of bleeding, such as: Tell your doctor if you take any of these medicines. If you miss a dose of ELIQUIS, take it as soon as you remember, and do not take more than one dose at the same time. This is especially important if youre taking multiple drugs. While taking ELIQUIS, you may bruise more easily and it may take longer than usual for any bleeding to stop. Examples of these include broccoli and, Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. None of it's unbearable (yet). If you have symptoms of a severe allergic reaction, such as swelling or trouble breathing, call 911 or your local emergency number right away. Also, drug rashes dont tend to cause any other symptoms. Apixaban may increase the risk of bleeding in the pregnant woman, the unborn baby, and the newborn baby. All rights reserved. The ELIQUIS (apixaban) Starter Kit (PDF), The ELIQUIS (apixaban) Dosing Guide (PDF), The ELIQUIS (apixaban) Discussion Guide (PDF). However, if it does, it could cause side effects, including serious bleeding, in a child whos breastfed. Both these effects of Eliquis can increase your risk of bleeding. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Get medical help right away if you have any of the following symptoms: Talk to your doctor about any side effect that may be bothering you or that does not go away. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. As such, the most common side effects of Eliquis include: Bleeding Bruising more easily than normal Anemia Other common side effects of Eliquis may include: Allergic reaction (skin rash, itching, flushing) Fatigue Nausea Headaches Dizziness The study is based on apixaban (the active ingredients of Eliquis). The Food and Drug Administration (FDA) has approved it to treat and help prevent certain dangerous blood clots. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. Take ELIQUIS exactly as prescribed by your doctor. 1-800-FDA-1088. Canada residents can call a provincial poison control center. ELIQUIS may need to be stopped prior to surgery or a medical or dental procedure. This is the most serious warning from the Food and Drug Administration (FDA). When leaving the hospital following hip or knee replacement, be sure that you will have ELIQUIS available to avoid missing any doses. Eliquis may not be right for you if you have certain medical conditions. People taking this medication may bleed near the spinal cord after certain spinal procedures. If you have a liver problem, talk with your doctor about whether Eliquis is right for you. Bristol Myers Squibb and Pfizer are not responsible for the content of such other sites and shall not be liable for any damages or injury arising from users access to such sites. To learn more about conditions that can affect the safety of Eliquis, see the Precautions for Eliquis section below. If you need Adobe Reader, click the link below to download the free readerLink to Adobe Reader Download page. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). What are the possible serious side effects of ELIQUIS? Additional symptoms are severe and can involve the internal organs, such as: fever swollen lymph nodes facial swelling. Examples include: If your doctor confirms youve had a mild allergic reaction to Eliquis, theyll decide if you should continue using it. Some drug rashes are severe and require emergency medical treatment. Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking apixaban and each time you get a refill. If you get this reaction, it will usually happen soon after you take a dose of ELIQUIS. Examples of mild side effects that have been reported with Eliquis include: In most cases, these side effects should be temporary. Do not stop taking apixaban unless directed by your doctor. Eliquis hasnt been studied in people with an artificial heart valve. It's important to keep the area clean and dry. In fact, Eliquis has a boxed warning for the risk of blood clots if you stop Eliquis too early. Physical examination revealed diffuse palpable tender non-blanching violaceous coalescent macules and patches on both thighs and calves ( figure 1) with purple bullae overlying a patch on the left dorsal fifth toe and the right medial calf. If youd like to learn more about Eliquis, talk with your doctor or pharmacist. If youre concerned about side effects that you may have while taking a higher dosage of Eliquis, talk with your doctor or pharmacist.